The blood brain barrier (Drugs) 1. Antidepressants: These kind of durgs are prescribed to people who just can't seem to get happy on their own. Like wise in some cases the drug may make it worst. And can be addictive for the reason your body feels the need to keep taking them to be happy. So in that case you and your body feels it can not get happy on its own. And there are many other side effects like death or dry mouth. Some in the long run you will be happy, but some times it will worsen may want to kill your self. Or you just can't live without them. Antidepressants can be life savers or bringers of death and some times a way to control people making them more friendly and controlable. 2. MARIJUANA (Cannabis): There has been many health beifites to smoking pot. But it also can mess up your nervous system by making reaction timing slower. Aslo effects sort trem memory. Parts effected are frontal lobe, medulla oblongata, and the temporal lobe.